Journal article
A Mycoses Study Group International Prospective Study of Phaeohyphomycosis: An Analysis of 99 Proven/Probable Cases
SG Revankar, JW Baddley, SCA Chen, CA Kauffman, M Slavin, JA Vazquez, C Seas, MI Morris, MH Nguyen, S Shoham, GR Thompson, BD Alexander, J Simkins, L Ostrosky-Zeichner, K Mullane, G Alangaden, DR Andes, OA Cornely, K Wahlers, SR Lockhart Show all
Open Forum Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2017
DOI: 10.1093/ofid/ofx200
Open access
Abstract
Background: Phaeohyphomycosis is infection caused by dematiaceous, or darkly pigmented, fungi. The spectrum of disease is broad, and optimal therapy remains poorly defined. The Mycoses Study Group established an international case registry of patients with proven/probable phaeohyphomycosis with the goal of improving the recognition and management of these infections. Methods: Patients from 18 sites in 3 countries were enrolled from 2009-2015. Cases were categorized as local superficial, local deep (pulmonary, sinus, osteoarticular infections), and disseminated infections. End points were clinical response (partial and complete) and all-cause mortality at 30 days and end of follow-up. Results..
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Funding Acknowledgements
This work was supported by the Mycoses Study Group, Astellas, Gilead, and Merck.