Journal article

Distinguishing schizophrenia spectrum from non-spectrum disorders among young patients with first episode psychosis and at high clinical risk: The role of basic self-disturbance and neurocognition

Jessica Spark, Lukasz Gaweda, Kelly Allott, Jessica A Hartmann, Bradley N Jack, Dan Koren, Suzie Lavoie, Emily Li, Patrick D McGorry, Josef Parnas, Andrea Polari, Louis A Sass, Thomas Whitford, Barnaby Nelson

SCHIZOPHRENIA RESEARCH | ELSEVIER | Published : 2021

Abstract

INTRODUCTION: The distinction between the schizophrenia spectrum and other types of disorders may be clinically relevant in terms of its predictive validity as suggested by studies showing schizophrenia spectrum patients have more unfavourable outcomes compared to other psychotic disorders. The present study aimed to investigate whether basic self-disturbances and neurocognitive processes that have been linked to psychosis risk have discriminative power for schizophrenia spectrum disorders in patients presenting with first episode psychosis (FEP) and at ultra-high risk for psychosis (UHR). METHODS: 38 FEP patients, 48 UHR patients, and 33 healthy controls were assessed for basic self-disturb..

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