Distinguishing schizophrenia spectrum from non-spectrum disorders among young patients with first episode psychosis and at high clinical risk: The role of basic self-disturbance and neurocognition
Jessica Spark, Lukasz Gaweda, Kelly Allott, Jessica A Hartmann, Bradley N Jack, Dan Koren, Suzie Lavoie, Emily Li, Patrick D McGorry, Josef Parnas, Andrea Polari, Louis A Sass, Thomas Whitford, Barnaby Nelson
SCHIZOPHRENIA RESEARCH | ELSEVIER | Published : 2021
INTRODUCTION: The distinction between the schizophrenia spectrum and other types of disorders may be clinically relevant in terms of its predictive validity as suggested by studies showing schizophrenia spectrum patients have more unfavourable outcomes compared to other psychotic disorders. The present study aimed to investigate whether basic self-disturbances and neurocognitive processes that have been linked to psychosis risk have discriminative power for schizophrenia spectrum disorders in patients presenting with first episode psychosis (FEP) and at ultra-high risk for psychosis (UHR). METHODS: 38 FEP patients, 48 UHR patients, and 33 healthy controls were assessed for basic self-disturb..View full abstract
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Awarded by NHMRC
The study was funded by a Brain & Behavior Research Foundation (NARSAD) Independent Investigator Award (BN). LG was supported by the Polish National Agency for Academic Exchange (The Bekker Programme). BN was supported by an NHMRC Senior Research Fellowship (1137687). KA was supported by an NHMRC Career Development Fellowship (1141207).