Novel tissue interactions support the evolution of placentation
Oliver W Griffith
JOURNAL OF MORPHOLOGY | WILEY | Published : 2021
Organ development occurs through the coordinated interaction of distinct tissue types. So, a question at the core of understanding the evolution of new organs is, how do new tissue-tissue signalling networks arise? The placenta is a great model for understanding the evolution of new organs, because placentas have evolved repeatedly, evolved relatively recently in some lineages, and exhibit intermediate forms in extant clades. Placentas, like other organs, form from the interaction of two distinct tissues, one maternal and one fetal. If each of these tissues produces signals that can be received by the other, then the apposition of these tissues is likely to result in new signalling dynamics ..View full abstract
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Awarded by Australian Research Council
This work was supported by the Australian Research Council (DE180100306).