Bioavailable fluoride in calcium-containing dentifrices
Peiyan Shen, James R Fernando, Yi Yuan, Glenn D Walker, Coralie Reynolds, Eric C Reynolds
SCIENTIFIC REPORTS | NATURE RESEARCH | Published : 2021
Calcium added to dentifrices can complex with fluoride ions to reduce intra-oral bioavailability and therefore efficacy in preventing dental caries. Six commercially available dentifrices containing different types of calcium and fluoride were analyzed for total and bioavailable fluoride levels by adding 10 g of dentifrice to 30 mL of distilled deionized water and mixing vigorously for 1 min to simulate toothbrushing. One milliliter of the dentifrice/water slurry was immediately centrifuged and the supernatant removed for bioavailable fluoride analysis and the mixed slurry prior to centrifugation used for total fluoride analysis using a modified microdiffusion method. The concentration of fl..View full abstract
Awarded by Australian Government Department of Industry, Innovation and Science
This study was supported by the Australian Government Department of Industry, Innovation and Science grant 20080108.