Journal article

How common are seizures in the heidenhain variant of creutzfeldt-jakob disease? A case report and systematic review

Subramanian Muthusamy, Priya Garg, Ronil Chandra, Udaya Seneviratne

JOURNAL OF CLINICAL NEUROSCIENCE | ELSEVIER SCI LTD | Published : 2021

Abstract

The Heidenhain variant of Creutzfeld-Jakob disease (HvCJD) is a relentlessly progressive and fatal neurodegenerative disorder characterised by prominent visual features early in its clinical course. However, seizures are uncommonly reported in HvCJD. The case history of a patient admitted to our institution with HvCJD and seizures is described followed by a systematic review of the association between HvCJD and seizures. A systematic search of the databases Medline, PubMed, and PsycInfo was conducted, from inception to November 2019, using keywords relating to 'Creutzfeldt-Jakob disease' and 'Heidenhain variant', to ascertain the frequency of seizures in HvCJD, as well as, seizure semiology ..

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