Temporal patterns in the first unprovoked seizure
Shuyu Wang, Ray Boston, Nicholas Lawn, Udaya Seneviratne
EPILEPSY & BEHAVIOR | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2021
OBJECTIVE: Cyclic phenomena in epilepsy are well recognized. We investigated a multicenter cohort of unprovoked first seizure presentations to determine whether seizures have a preponderance to occur in: a particular time of the day, a particular day of the week, a particular month of the year, day time versus night time, and wakefulness versus sleep. METHODS: We retrospectively studied adults who presented with a first-ever unprovoked seizure to the First Seizure Clinic at two tertiary centers in Australia. Seizure onset time was obtained from the emergency department and ambulance documentations. Electro-clinical and neuroimaging findings were reviewed. We used histograms and Poisson regre..View full abstract
U. Seneviratne has received travel and speaker honoraria from Eisai Australia and LivaNova Australia. N. Lawn has received research funding support, consultancy fees and speaker honorariums from UCB and Eisai. This research funding is unrelated to this study. S. Wang has no conflict of interest to disclose. We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.