Gestational Folate and Offspring Bone Health; The Vitamin D in Pregnancy Study
Mia A Percival, Julie A Pasco, Sarah M Hosking, Lana J Williams, Kara L Holloway-Kew, Natalie K Hyde
CALCIFIED TISSUE INTERNATIONAL | SPRINGER | Published : 2021
Maternal nutritional intake, such as folate and folic acid supplementation, during pregnancy may affect offspring bone health during childhood. We aimed to determine the associations between maternal dietary and supplementary folate intake and offspring bone health measures, including fracture risk. Data were obtained from 160 of 475 mother-child pairs who had returned for the 11-year follow up of the Vitamin D in Pregnancy Study, an observational cohort study. Incident fractures were ascertained from radiological records and dual X-ray absorptiometry was used to measure bone mineral density and content at 11 years of age. Maternal dietary folate intake during pregnancy was determined by Foo..View full abstract
Awarded by NHMRC
This study has received funding from the National Health and Medical and Research Council (NHMRC) and Bupa Health Foundation. SMH and KLH-K were funded by an Alfred Deakin Postdoctoral Research Fellowship (Deakin University), LJW is supported by an NHMRC Career Development Fellowship (1064272) and a NHMRC Investigator Grant (1174060).