Journal article
The severe epilepsy syndromes of infancy: A population-based study
KB Howell, JL Freeman, MT Mackay, MC Fahey, J Archer, SF Berkovic, E Chan, G Dabscheck, S Eggers, M Hayman, J Holberton, RW Hunt, SE Jacobs, AJ Kornberg, RJ Leventer, S Mandelstam, JM McMahon, HC Mefford, J Panetta, J Riseley Show all
Epilepsia | WILEY | Published : 2021
DOI: 10.1111/epi.16810
Abstract
Objective: To study the epilepsy syndromes among the severe epilepsies of infancy and assess their incidence, etiologies, and outcomes. Methods: A population-based cohort study was undertaken of severe epilepsies with onset before age 18 months in Victoria, Australia. Two epileptologists reviewed clinical features, seizure videos, and electroencephalograms to diagnose International League Against Epilepsy epilepsy syndromes. Incidence, etiologies, and outcomes at age 2 years were determined. Results: Seventy-three of 114 (64%) infants fulfilled diagnostic criteria for epilepsy syndromes at presentation, and 16 (14%) had "variants" of epilepsy syndromes in which there was one missing or diffe..
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Awarded by National Institutes of Health
Funding Acknowledgements
University of Melbourne; Melbourne Children's Campus; National Health and Medical Research Council; National Institutes of Health, Grant/Award Number: NS069605