PO-231 CTXIII expression around single tumour cells of invasive breast carcinoma

Abstract

Introduction Studies of breast carcinoma indicated the presence of type I and III collagens localization at the invasion front of the tumour. Mesenchymal invasion accompanied by proteolysis, in particular collagens, and remodelling of tissue structures by matrix metalloprotases. Possible marker of this process is expression of Cross Linked C-telopeptide of Type III Collagen (CTX-III). The project is aimed to study frequency of CTX-III expression around different of single tumour cells subtypes of invasive breast carcinoma of no specific type. Material and methods Fourteen patients with invasive breast carcinoma of no specific type (IC NST, all molecular subtypes, T1-3N0-3M0) were enrolled in..