Conference Proceedings

A Simple Cleaning Intervention to Prevent Transmission of Carbapenemase-Producing Enterobacterales from Hospital Sinks

Jason Kwong, Marcel Leroi, Trudi Bannam, Deidre Edmonds, Elizabeth Grabsch, Shanti Narayanasamy, John Greenough, Courtney Lane, Marion Easton, Benjamin Howden, Paul Johnson, M Grayson

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | CAMBRIDGE UNIV PRESS | Published : 2020

Abstract

Background: A prolonged outbreak of carbapenemase-producing Serratia marcescens (CPSM) was identified in our quaternary healthcare center over a 2-year period from 2015 through 2017. A reservoir of IMP-4–producing S. marcescens in sink drains of clinical hand basins (CHB) was implicated in propagating transmission, supported by evidence from whole-genome sequencing (WGS). We assessed the impact of manual bioburden reduction intervention on further transmission of CPSM. Methods: Environmental sampling of frequently touched wet and dry areas around CPSM clinical cases was undertaken to identify potential reservoirs and transmission pathways. After identifying CHB as a source of CPSM, a widespr..

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