The genetic basis of inter-individual variation in recovery from traumatic brain injury
Daniel Cortes, Martin F Pera
npj Regenerative Medicine | NATURE RESEARCH | Published : 2021
Traumatic brain injury (TBI) is one of the leading causes of death among young people, and is increasingly prevalent in the aging population. Survivors of TBI face a spectrum of outcomes from short-term non-incapacitating injuries to long-lasting serious and deteriorating sequelae. TBI is a highly complex condition to treat; many variables can account for the observed heterogeneity in patient outcome. The limited success of neuroprotection strategies in the clinic has led to a new emphasis on neurorestorative approaches. In TBI, it is well recognized clinically that patients with similar lesions, age, and health status often display differences in recovery of function after injury. Despite t..View full abstract
D.C. is the recipient of a JAX Scholar's Award from the Jackson Laboratory.