Journal article

To Expand the Evidence Base About Harms from Tests and Treatments

Deborah Korenstein, Russell Harris, Adam G Elshaug, Joseph S Ross, Daniel J Morgan, Richelle J Cooper, Hyung J Cho, Jodi B Segal

Journal of General Internal Medicine | SPRINGER | Published : 2021

Abstract

Rigorous evidence about the broad range of harms that might be experienced by a patient in the course of testing and treatment is sparse. We aimed to generate recommendations for how researchers might more comprehensively evaluate potential harms of healthcare interventions, to allow clinicians and patients to better include this evidence in clinical decision-making. We propose seven domains of harms of tests and treatments that are relevant to patients: (1) physical impairment, (2) psychological distress, (3) social disruption, (4) disruption in connection to healthcare, (5) labeling, (6) financial impact, and (7) treatment burden. These domains will include a range of severity of harms and..

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Grants

Awarded by National Cancer Institute


Awarded by National Institute on Aging


Funding Acknowledgements

This project was not directly funded. DK's work was supported in part by a grant from the National Cancer Institute to Memorial Sloan Kettering Cancer Center (P30 CA008748-50). JBS reports support from K24 AG049036-01A1 from the National Institute on Aging.