Journal article

Learning from scaling up ultra-rapid genomic testing for critically ill children to a national level

Stephanie Best, Helen Brown, Sebastian Lunke, Chirag Patel, Jason Pinner, Christopher P Barnett, Meredith Wilson, Sarah A Sandaradura, Belinda McClaren, Gemma R Brett, Jeffrey Braithwaite, Zornitza Stark

NPJ GENOMIC MEDICINE | NATURE RESEARCH | Published : 2021

Abstract

In scaling up an ultra-rapid genomics program, we used implementation science principles to design and investigate influences on implementation and identify strategies required for sustainable "real-world" services. Interviews with key professionals revealed the importance of networks and relationship building, leadership, culture, and the relative advantage afforded by ultra-rapid genomics in the care of critically ill children. Although clinical geneticists focused on intervention characteristics and the fit with patient-centered care, intensivists emphasized the importance of access to knowledge, in particular from clinical geneticists. The relative advantage of ultra-rapid genomics and t..

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Grants

Awarded by NHMRC Targeted Call for Research grant


Funding Acknowledgements

This research was funded by an NHMRC Targeted Call for Research grant (GNT1113531): "Preparing Australia for Genomic Medicine". The research conducted at the Murdoch Children's Research Institute was supported by the Victorian Government's Operational Infrastructure Support Program.