Journal article

Sarcopenia, Low Handgrip Strength, and Low Absolute Muscle Mass Predict Long-Term Mortality in Older Hospitalized Patients: An Observational Inception Cohort Study

Kira Scheerman, Carel GM Meskers, Sjors Verlaan, Andrea B Maier

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION | ELSEVIER SCIENCE INC | Published : 2021

Abstract

OBJECTIVE: Sarcopenia is highly prevalent in hospitalized older patients and associated with short-term mortality. This study aimed to investigate whether sarcopenia and its measures handgrip strength (HGS) and muscle mass at hospital admission were associated with long-term mortality in a cohort of hospitalized older patients. DESIGN: Observational, prospective, longitudinal inception cohort study. SETTING AND PARTICIPANTS: Academic teaching hospital; patients age ≥70 years admitted to the internal medicine, acute admission, trauma, or orthopedic wards. METHODS: HGS and muscle mass were measured at admission using a hand dynamometer and bioelectrical impedance analysis. Sarcopenia was deter..

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Grants

Awarded by European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Grant


Funding Acknowledgements

This work was supported by European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 675003.