Journal article

Plasmon-induced enhancement of ptychographic phase microscopy via sub-surface nanoaperture arrays

Eugeniu Balaur, Guido A Cadenazzi, Nicholas Anthony, Alex Spurling, Eric Hanssen, Jacqueline Orian, Keith A Nugent, Belinda S Parker, Brian Abbey

NATURE PHOTONICS | NATURE RESEARCH | Published : 2021

Abstract

The invention of phase contrast microscopy revolutionized optics, enabling the visualization of highly optically transparent samples without the need for staining. The technique utilizes phase shifts within the sample and is routinely employed in the characterization of biological material and other weakly interacting objects. However, the demand for increased contrast and quantification has continued to drive research into more advanced approaches to phase imaging. Here, we demonstrate that the combination of ptychographic coherent diffractive imaging with plasmonically active metamaterials yields a massive enhancement of both the reconstructed phase and amplitude by exploiting near-field i..

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Grants

Funding Acknowledgements

We acknowledge support from the Australian Research Council through the ARC Centre of Excellence in Advanced Molecular Imaging and fellowship funding from the Victorian Cancer Agency (B.S.P.). B.A. acknowledges support from the La Trobe Biomedical and Environmental Sensor Technology (BEST) Research Centre. This work was performed in part at the Melbourne Centre for Nanofabrication (MCN) in the Victorian Node of the Australian National Fabrication Facility (ANFF).