Journal article
Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium
Ling-Wei Chen, Adrien M Aubert, Nitin Shivappa, Jonathan Y Bernard, Sara M Mensink-Bout, Aisling A Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Elzbieta Trafalska, Caroline L Relton, Sarah R Crozier, Nicholas C Harvey, Cyrus Cooper, Liesbeth Duijts, Barbara Heude, James R Hebert, Fionnuala M McAuliffe, Cecily C Kelleher Show all
PLOS MEDICINE | PUBLIC LIBRARY SCIENCE | Published : 2021
Abstract
BACKGROUND: Adverse birth outcomes are major causes of morbidity and mortality during childhood and associate with a higher risk of noncommunicable diseases in adult life. Maternal periconception and antenatal nutrition, mostly focusing on single nutrients or foods, has been shown to influence infant birth outcomes. However, evidence on whole diet that considers complex nutrient and food interaction is rare and conflicting. We aim to elucidate the influence of whole-diet maternal dietary inflammatory potential and quality during periconceptional and antenatal periods on birth outcomes. METHODS AND FINDINGS: We harmonized and pooled individual participant data (IPD) from up to 24,861 mother-c..
View full abstractGrants
Awarded by European Union's Horizon 2020 research and innovation programme under the ERA-Net Cofund of the Joint Programming Initiative Healthy Diet for Healthy Life (JPI-HDHL)
Awarded by Science Foundation Ireland, Ireland
Awarded by UK Biotechnology and Biological Sciences Research Council
Awarded by National Centre for Research and Development
Awarded by ZonMW The Netherlands
Awarded by ALPHABET project
Awarded by French National Agency of Research
Funding Acknowledgements
This work was supported by an award from the European Union's Horizon 2020 research and innovation programme under the ERA-Net Cofund of the Joint Programming Initiative Healthy Diet for Healthy Life (JPI-HDHL) (http://www.healthydietforhealthylife.eu) action number 696295 (Biomarkers for Nutrition and Health). Co-funding was provided by Science Foundation Ireland, Ireland (Grant Number SFI/16/ERA-HDHL/3360) to CMP (used to support LWC's salary); the UK Biotechnology and Biological Sciences Research Council (ERA-HDHL Biomarkers: BBSRC: BB/P028179/1 and BB/P028187/1) to CLR and NCH; National Centre for Research and Development (ERA-HDHL/01/ALPHABET/1/2017) to KP (used to partially support KP's and WH's salaries); the ZonMW The Netherlands (no 529051014; 2017) ALPHABET project (no 696295; 2017)) to LD; the French National Agency of Research (reference AnrR16227KK) to BH (used to support AMA's and JYB's salaries). Cohort-specific sources of funding are listed in S1 Text. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.