Journal article

Posttubercular syringomyelia in HIV-infected patients: A report of 10 cases and literature review

Suzaan Marais, Izanne Roos, Ayesha Mitha, Vinod Patel, Ahmed I Bhigjee

JOURNAL OF THE NEUROLOGICAL SCIENCES | ELSEVIER SCIENCE BV | Published : 2018

Abstract

OBJECTIVES: To describe the clinical presentation, spinal magnetic resonance imaging (MRI) findings and outcome of HIV-infected patients with tuberculosis (TB)-associated syringomyelia and to compare these findings between all HIV-infected and -uninfected cases published in the literature. METHODS: A retrospective observational study conducted over a 12.5-year period at a public-sector referral hospital in South Africa. HIV-infected adults with neurological TB in whom MRI confirmed a syrinx were included. We searched PubMed to identify all published syringomyelia cases. RESULTS: Ten patients were enrolled. Syringomyelia complicated neurological TB within four years of initial diagnosis in al..

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