Thesis / Dissertation

The effect of sodium on sympathetic nervous system activity and endothelial function in people with type 2 diabetes

Sara Baqar, Elif Ekinci (ed.)

Published : 2020

Abstract

Lowering dietary sodium intake is recommended by public health bodies to lower blood pressure with the ultimate aim of reducing cardiovascular-related disease. However, lower sodium intake has been demonstrated in observational studies to be associated with adverse health outcomes such as higher cardiovascular-related morbidity and mortality in people with type 2 diabetes. They may be due to pleiotropic effects of sodium lowering, such as activation of the renin-angiotensin-aldosterone system (RAAS) and increases in circulating adrenaline and noradrenaline. Dedicated intervention trials are lacking but greatly needed to investigate the complex role of sodium on cardiovascular outcomes furthe..

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University of Melbourne Researchers