Journal article

Impact of moderate and late preterm birth on neurodevelopment, brain development and respiratory health at school age: protocol for a longitudinal cohort study (LaPrem study)

Jeanie Cheong, Kate Lillian Iona Cameron, Deanne Thompson, Peter J Anderson, Sarath Ranganathan, Ross Clark, Benjamin Mentiplay, Alice Burnett, Katherine Lee, Lex William Doyle, Alicia J Spittle

BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2021

Abstract

INTRODUCTION: Children born moderate to late preterm (MLP, 32-36 weeks' gestation) account for approximately 85% of all preterm births globally. Compared with children born at term, children born MLP are at increased risk of poor neurodevelopmental outcomes. Despite making up the largest group of preterm children, developmental outcomes of children born MLP are less well studied than in other preterm groups. This study aimed to (1) compare neurodevelopmental, respiratory health and brain magnetic resonance imaging (MRI) outcomes between children born MLP and term at 9 years of age; (2) examine the differences in brain growth trajectory from infancy to 9 years between children born MLP and te..

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Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by Centre of Research Excellence


Awarded by Career Development Fellowship


Awarded by Medical Research Future Fund


Funding Acknowledgements

This study is supported by grants from the National Health and Medical Research Council of Australia (project grant #1161305), Centre of Research Excellence (#1153176), Career Development Fellowship (#1160003 to DT, 1127984 to KL, #1108714 to AJS, Leadership Fellowship #1176077 to PJA), Medical Research Future Fund (Career Development Fellowship #1141354 to JC) and the Victorian Government's Operational Infrastructure Support Program.