Journal article

Child health after preimplantation genetic testing

Sharon Lewis, David J Amor, Anne Glynn, Leeanda Wilton, Jane Halliday

REPRODUCTIVE BIOMEDICINE ONLINE | ELSEVIER SCI LTD | Published : 2021

Abstract

RESEARCH QUESTION: Despite the increasing use of preimplantation genetic testing (PGT) for aneuploidy and monogenic diseases, for children conceived using PGT there is limited follow-up beyond 2 years of age. This study examined the health, well-being and development of school-aged children (5-8 years old) conceived following PGT. DESIGN: Retrospective cohort study of children conceived after IVF with PGT (exposed cohort) and children conceived after IVF without PGT (unexposed cohort) at two IVF clinics in Melbourne, born between 2000 and 2008, recruited with a 1:2 ratio. Mothers of the children completed a questionnaire asking child-specific questions regarding health and well-being, mental..

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Grants

Funding Acknowledgements

The authors thank Ms Caroline Cox, Ms Kay Oke, Ms Sue Breheny, Dr Elissa Osborne and Ms Vivien McLachlan for assistance with data collection. This work was funded in part by Monash IVF Research and Education Foundation and Melbourne IVF. This work was made possible through the Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIISS.