Journal article
Lung ultrasound during newborn resuscitation predicts the need for surfactant therapy in very- and extremely preterm infants
S Badurdeen, COF Kamlin, SR Rogerson, SC Kane, GR Polglase, SB Hooper, PG Davis, DA Blank
Resuscitation | ELSEVIER IRELAND LTD | Published : 2021
Abstract
Introduction: Early identification of infants requiring surfactant therapy improves outcomes. We evaluated the accuracy of delivery room lung ultrasound (LUS) to predict surfactant therapy in very- and extremely preterm infants. Methods: Infants born at <320/7 weeks were prospectively enrolled at 2 centres. LUS videos of both sides of the chest were obtained 5−10 min, 11−20 min, and 1−3 h after birth. Clinicians were masked to the results of the LUS assessment and surfactant therapy was provided according to local guidelines. LUS videos were graded blinded to clinical data. Presence of unilateral type 1 (‘whiteout’) LUS or worse was considered test positive. Receiver Operating Characteristic..
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Grants
Awarded by Australian Government
Funding Acknowledgements
This study was conducted with grant support from the GE/Emergency Medicine Foundation (US) Bright Ideas Point of Care Global Challenge (2017) under the name: "The Description of Lung ultrasound From Initial Neonatal transition in very preterm infants" (The DOLFIN Jr Study). The study authors receive funding from the National Health and Medical Research Council (NH&MRC) Program Grant (#606789), Fellowships (SH: APP545921, GP: APP1105526, PD: APP1059111), and Australian Government Research Training Program Scholarships (SB and SK). The funders had no role in the in the study design, in the collection, analysis and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication.