Journal article
Incidence and management of metabolic acidosis with sodium bicarbonate in the ICU: An international observational study
T Fujii, AA Udy, A Nichol, R Bellomo, AM Deane, K El-Khawas, N Thummaporn, A Serpa Neto, H Bergin, R Short-Burchell, CM Chen, KH Cheng, KC Cheng, C Chia, FF Chiang, NK Chou, T Fazio, PK Fu, V Ge, Y Hayashi Show all
Critical Care | BMC | Published : 2021
Abstract
Background: Metabolic acidosis is a major complication of critical illness. However, its current epidemiology and its treatment with sodium bicarbonate given to correct metabolic acidosis in the ICU are poorly understood. Method: This was an international retrospective observational study in 18 ICUs in Australia, Japan, and Taiwan. Adult patients were consecutively screened, and those with early metabolic acidosis (pH < 7.3 and a Base Excess < –4 mEq/L, within 24-h of ICU admission) were included. Screening continued until 10 patients who received and 10 patients who did not receive sodium bicarbonate in the first 24 h (early bicarbonate therapy) were included at each site. The primary outco..
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Awarded by Jikei University School of Medicine
Funding Acknowledgements
This study was supported by Jikei University Research Grant to TF. The funding body did not take any role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.