Journal article
What Is the “Optimal” Target Mismatch Criteria for Acute Ischemic Stroke?
C Chen, MW Parsons, CR Levi, NJ Spratt, L Lin, T Kleinig, K Butcher, X Cheng, Q Dong, B O'Brien, RI Avivi, M Krause, PN Sylaja, P Choi, S Bhuta, C Yin, J Yang, P Wang, W Qiu, A Bivard
Frontiers in Neurology | Published : 2021
Open access
Abstract
We aimed to compare Perfusion Imaging Mismatch (PIM) and Clinical Core Mismatch (CCM) criteria in ischemic stroke patients to identify the effect of these criteria on selected patient population characteristics and clinical outcomes. Patients from the INternational Stroke Perfusion Imaging REgistry (INSPIRE) who received reperfusion therapy, had pre-treatment multimodal CT, 24-h imaging, and 3 month outcomes were analyzed. Patients were divided into 3 cohorts: endovascular thrombectomy (EVT), intravenous thrombolysis alone with large vessel occlusion (IVT-LVO), and intravenous thrombolysis alone without LVO (IVT-nonLVO). Patients were classified using 6 separate mismatch criteria: PIM-using ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
NS was the recipient of a co-funded NHMRC/NHF Career Development/Future Leader Fellowship APP1110629/ 100827. XC and QD were supported by National Key R&D Program of China 2017YFC1308201.