Longitudinal whole-genome based comparison of carriage and infection associated Staphylococcus aureus in northern Australian dialysis clinics
Deborah C Holt, Tegan M Harris, Jaquelyne T Hughes, Rachael Lilliebridge, David Croker, Sian Graham, Heather Hall, Judith Wilson, Steven YC Tong, Phillip M Giffard
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2021
BACKGROUND: The study objective was to reveal reservoirs potentially leading to Staphylococcus aureus infections in haemodialysis clinic clients in the tropical north of the Australian Northern Territory (NT). This client population are primarily Aboriginal Australians who have a greater burden of ill health than other Australians. Reservoir identification will enhance infection control in this client group, including informing potential S. aureus decolonisation strategies. METHODS AND FINDINGS: The study participants were 83 clients of four haemodialysis clinics in the Darwin region of the NT, and 46 clinical staff and researchers who had contact with the clinic clients. The study design wa..View full abstract
Awarded by National Health and Medical Research Council of Australia (NHMRC)
Awarded by NHMRC Early Career Fellowship
This research was funded by the National Health and Medical Research Council of Australia (NHMRC) https://www.nhmrc.gov.au/(Project Grant 1022782). JTH was supported by a Jacquot Research Establishment Award from the Royal Australian College of Physicians (https://www.racp.edu.au/about/foundation/research-awards-andcareer-grants/research-establishment-awards) and an NHMRC Early Career Fellowship (#1092576). ST is a NHMRC Career Development Fellow (#1145033) The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.