Journal article

Symptoms and laboratory manifestations of mild COVID-19 in a repatriated cruise ship cohort

CR Bailie, L Franklin, S Nicholson, F Mordant, C Alpren, T Stewart, C Barnes, A Fox, J Druce, K Subbarao, M Catton, A van Diemen, SG Sullivan

Epidemiology and Infection | CAMBRIDGE UNIV PRESS | Published : 2021

Abstract

Much of our current understanding about novel coronavirus disease 2019 (COVID-19) comes from hospitalised patients. However, the spectrum of mild and subclinical disease has implications for population-level screening and control. Forty-nine participants were recruited from a group of 99 adults repatriated from a cruise ship with a high incidence of COVID-19. Respiratory and rectal swabs were tested by polymerase chain reaction (PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sera were tested for anti-SARS-CoV-2 antibodies by enzyme-linked immunosorbent assay (ELISA) and microneutralisation assay. Symptoms, viral shedding and antibody response were examined. Forty-five..

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