Symptoms and laboratory manifestations of mild COVID-19 in a repatriated cruise ship cohort
CR Bailie, L Franklin, S Nicholson, F Mordant, C Alpren, T Stewart, C Barnes, A Fox, J Druce, K Subbarao, M Catton, A van Diemen, SG Sullivan
Epidemiology and Infection | CAMBRIDGE UNIV PRESS | Published : 2021
Much of our current understanding about novel coronavirus disease 2019 (COVID-19) comes from hospitalised patients. However, the spectrum of mild and subclinical disease has implications for population-level screening and control. Forty-nine participants were recruited from a group of 99 adults repatriated from a cruise ship with a high incidence of COVID-19. Respiratory and rectal swabs were tested by polymerase chain reaction (PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sera were tested for anti-SARS-CoV-2 antibodies by enzyme-linked immunosorbent assay (ELISA) and microneutralisation assay. Symptoms, viral shedding and antibody response were examined. Forty-five..View full abstract
This study was supported by the Victorian Department of Health and Human Services. The Melbourne WHO Collaborating Centre for Reference and Research on Influenza is supported by the Australian Government Department of Health.