Journal article

Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer: A pooled analysis of data from two prospective cohort studies

Harindra Jayasekara, Robert J MacInnis, Leila Lujan-Barroso, Ana-Lucia Mayen-Chacon, Amanda J Cross, Bengt Wallner, Domenico Palli, Fulvio Ricceri, Valeria Pala, Salvatore Panico, Rosario Tumino, Tilman Kuehn, Rudolf Kaaks, Kostas Tsilidis, Maria-Jose Sanchez, Pilar Amiano, Eva Ardanaz, Maria Dolores Chirlaque Lopez, Susana Merino, Joseph A Rothwell Show all



Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne Collaborative Cohort Study. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated for incident stomach cancer in relation to lifetime alcohol intake and group-based life course intake trajectories, adjusted for potential confounders including Helicobacter pylori infection. In a..

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Awarded by Australian National Health and Medical Research Council

Awarded by Cancer Research UK

Awarded by French Ministry of Health

Awarded by Medical Research Council (UK)

Funding Acknowledgements

Australian National Health and Medical Research Council, Grant/Award Numbers: 1074383, 209057, 396414, GNT1163120; Cancer Council Victoria (Australia); Cancer Research UK, Grant/Award Numbers: C570/A16491, C8221/A19170, C864/A14136; Catalan Institute of Oncology - ICO (Spain); Danish Cancer Society; Deutsche Krebshilfe, the Deutsches Krebsforschungszentrum (Germany); Dutch Ministry of Public Health, Welfare and Sports; European Commission (Directorate General for Health and Consumer Affairs); Foundation for Alcohol Research and Education (Australia); French Ministry of Health, Grant/Award Number: Grant GR-IARC-2003-09-12-01; Health Research Fund (FIS) -Instituto de Salud Carlos III (ISCIII), Regional Governments of Andalucia, Asturias, Basque Country, Murcia and Navarra; Hellenic Health Foundation (Greece); Hellenic Ministry of Health and Social Solidarity (Greece); Institut National de la Sante et de la Recherche Medicale (France); Italian Association for Research on Cancer and the National Research Council (Italy); Ligue Contre le Cancer (France); LK Research Funds, Dutch Prevention Funds, the Dutch Zorg Onderzoek Nederland; Medical Research Council (UK), Grant/Award Numbers: MC-UU_12015/1, MR/M012190/1, MR/N003284/1; Mutuelle Generale de l'Education Nationale; National Institute for Public Health and the Environment (RIVM) (the Netherlands); Netherlands Cancer Registry; Stavros Niarchos Foundation (Greece); Stroke Association, the British Heart Foundation, the Department of Health, the Food Standards Agency and the Wellcome Trust (UK); Swedish Cancer Society, the Swedish Scientific Council and the Regional Government of Skane (Sweden); the Federal Ministry of Education and Research (Germany); VicHealth (Australia); World Cancer Research Fund and Statistics Netherlands (the Netherlands); the Institut Gustave Roussy