Acute electrical, autonomic and structural effects of binge drinking: Insights into the 'holiday heart syndrome'
Aleksandr Voskoboinik, Conor McDonald, David Chieng, Jessica O'Brien, Sarah Gutman, Phillip Ngu, Hariharan Sugumar, Geoffrey Wong, Jonathan M Kalman, Andrew J Taylor, Peter M Kistler
INTERNATIONAL JOURNAL OF CARDIOLOGY | ELSEVIER IRELAND LTD | Published : 2021
BACKGROUND: Binge drinking is a common atrial fibrillation (AF) trigger, however the mechanisms are poorly understood. OBJECTIVE: To investigate the effects of alcohol intoxication and hangover with rhythm monitoring and cardiac MRI. METHODS: Patients underwent serial cardiac MRI pre- and post-binge with continuous Holter monitoring. Time periods analyzed: baseline (24 h pre-binge), consumption, hangover (0- 24 h post-consumption) and post-hangover (24-48 h post-consumption). RESULTS: 50 patients (age 49 ± 15 years, 40% paroxysmal AF) completed the study (intake 8.4 ± 3.1 standard drinks). Mean heart rate increased from 72 ± 10 to 80 ± 13 beats per minute (bpm) during consumption (p < 0.001)..View full abstract
Dr. Voskoboinik is supported by a National Heart Foundation of Australia Early Career Fellowship. Prof Kalman is supported by a NHMRC practitioner fellowship.