Journal article

The psychometric validity of the Montgomery-Asberg Depression Rating Scale (MADRS) in recent onset schizophrenia spectrum disorders

Sarah E Herniman, Sue M Cotton, Kelly A Allott, Lisa J Phillips, Stephen J Wood

SCHIZOPHRENIA RESEARCH | ELSEVIER | Published : 2021

Abstract

Earlier recognition and accurate assessment of depressive symptoms is important to improving outcomes in individuals with recent-onset schizophrenia spectrum disorders (termed SSD hereafter)-regardless of whether positive psychotic symptoms are present or have resolved. The Montgomery-Åsberg Depression Rating Scale (MADRS) is frequently used to assess depressive symptoms in SSD, but no study has examined the psychometric validity of MADRS scores in individuals exclusively with SSD and sub-grouped by those with and without positive psychotic symptoms. This study involved baseline data from the Psychosis Recent Onset GRoningen Survey (PROGR-S). Measures used were: MADRS, depressive and negativ..

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Grants

Awarded by National Health and Medical Research Council Senior Research Fellowship


Awarded by Career Development Fellowship from the NHMRC


Funding Acknowledgements

SEH is supported by a Research Training Program Scholarship awarded by the Australian Commonwealth Government. SMC is supported by a National Health and Medical Research Council Senior Research Fellowship (APP1136344). KA is supported by a Career Development Fellowship from the NHMRC (1141207). The framework of the PROGR-S-cohort is supported by the University Centre of Psychiatry of the University Medical Centre Groningen, Lentis Mental Health Institute, Groningen, and the Rob Giel Research Centre, Groningen, The Netherlands.