Journal article

Endoscopic Dilatation of Crohn's Anastomotic Strictures is Effective in the Long Term, and Escalation of Medical Therapy Improves Outcomes in the Biologic Era

Nik Sheng Ding, Wai Man Yip, CH Choi, Brian Saunders, Siwan Thomas-Gibson, Naila Arebi, Adam Humphries, Ailsa Hart

JOURNAL OF CROHNS & COLITIS | OXFORD UNIV PRESS | Published : 2016

Abstract

BACKGROUND AND AIMS: To investigate the long-term efficacy of endoscopic dilatation of Crohn's anastomotic strictures and to identify risk and protective factors associated with the need for repeat dilatation or surgery. METHODS: A total of 54 patients who had endoscopic balloon dilatations for anastomotic Crohn's strictures between 2004 and 2009, with follow-up until June 2014, were identified from a single tertiary center. The primary end points were repeat dilatation or surgical resection, and the impact of radiology, medical therapy, and endoscopic data on these outcomes was analysed with Cox proportional hazards analysis. RESULTS: A total of 151 dilatations were performed on patients wi..

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University of Melbourne Researchers