Journal article

Infertility and fecundity loss of Wolbachia-infected Aedes aegypti hatched from quiescent eggs is expected to alter invasion dynamics

Meng-Jia Lau, Perran A Ross, Ary A Hoffmann

PLoS Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2021


The endosymbiotic bacterium Wolbachia shows viral blocking in its mosquito host, leading to its use in arboviral disease control. Releases with Wolbachia strains wMel and wAlbB infecting Aedes aegypti have taken place in several countries. Mosquito egg survival is a key factor influencing population persistence and this trait is also important when eggs are stored prior to releases. We therefore tested the viability of mosquitoes derived from Wolbachia wMel and wAlbB-infected as well as uninfected eggs after long-term storage under diurnal temperature cycles of 11-19°C and 22-30°C. Eggs stored at 11-19°C had higher hatch proportions than those stored at 22-30°C. Adult Wolbachia density decli..

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University of Melbourne Researchers


Awarded by National Health and Medical Research Council

Awarded by Wellcome Trust

Funding Acknowledgements

AAH was supported by the National Health and Medical Research Council (1132412, 1118640, and the Wellcome Trust (108508, The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.