Journal article

Association between ambient air pollution and development and persistence of atopic and non-atopic eczema in a cohort of adults

Diego J Lopez, Caroline J Lodge, Dinh S Bui, Nilakshi T Waidyatillake, John C Su, Jenny L Perret, Luke D Knibbs, Bircan Erbas, Paul S Thomas, Garun S Hamilton, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage, Gayan Bowatte, Adrian J Lowe

ALLERGY | WILEY | Published : 2021


BACKGROUND: There is limited information on risk factors for eczema in adults. Recent evidence suggests that air pollution may be associated with increased incidence of eczema in adults. We aimed to assess this possible association. METHODS: Ambient air pollution exposures (distance from a major road, nitrogen dioxide [NO2 ], fine particulate matter with an aerodynamic diameter ≤2.5 µm [PM2.5 ]) were assessed for the residential address of Tasmanian Longitudinal Health Study participants at ages 43 and 53 years. Eczema incidence (onset after age 43 years), prevalence (at 53 years), and persistence were assessed from surveys, while IgE sensitization was assessed using skin prick tests. The pr..

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Awarded by National Health and Medical Research Council (NHMRC) of Australia

Funding Acknowledgements

This study was supported by the National Health and Medical Research Council (NHMRC) of Australia (research grants 299901 and 1021275); the University of Melbourne, the Clifford Craig Medical Research Trust of Tasmania; the Victorian, Queensland and Tasmanian Asthma Foundations; Royal Hobart Hospital; Helen MacPherson Smith Trust; GlaxoSmithKline; and John L Hopper. DL acknowledges the contribution of the Melbourne Research Scholarship (Fee offset) and Becas Carlos Antonio Lopez scholarship to undertake this study which relates to his doctoral candidature at the University of Melbourne. The funding agencies had no direct role in the conduct of the study; the collection, management, statistical analysis, and interpretation of the data; or the preparation or approval of the manuscript.