Journal article

Changes over time in quality of life of school-aged children born extremely preterm: 1991-2005

S Peart, JLY Cheong, G Roberts, N Davis, PJ Anderson, LW Doyle

Archives of Disease in Childhood Fetal and Neonatal Edition | BMJ PUBLISHING GROUP | Published : 2021

Abstract

Objective To compare health-related quality of life (HRQOL) at 8 years in children born extremely preterm (EP) with contemporaneous term-born controls over three epochs: 1991-92, 1997 and 2005. Design Prospective recruitment of geographic cohorts across three distinct eras. Utilities were calculated from the parent-completed Health Utilities Index (HUI), version 2 (1991-92 and 1997 cohorts) and version 3 (2005 cohort). Differences in utilities >0.05 are clinically important. Setting The state of Victoria, Australia. Patients 475 EP (<28 weeks' gestation) and 570 term controls. Main outcome measures Utilities of children born EP compared with term controls within each era, and paired differen..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

Supported by grants from the National Health and Medical Research Council of Australia (Centre of Clinical Research Excellence #546519; Centres of Research Excellence #1060733 and #1153176; Project Grant #108702, Leadership Fellowship #1176077 to PJA), Medical Research Future Fund (Career Development Fellowship #1141354 to JC) and the Victorian Government's Operational Infrastructure Support Program.