Journal article

Prevalence of Sarcopenia Employing Population-Specific Cut-Points: Cross-Sectional Data from the Geelong Osteoporosis Study, Australia

Sophia X Sui, Kara L Holloway-Kew, Natalie K Hyde, Lana J Williams, Monica C Tembo, Sarah Leach, Julie A Pasco

JOURNAL OF CLINICAL MEDICINE | MDPI | Published : 2021

Abstract

BACKGROUND: Prevalence estimates for sarcopenia vary depending on the ascertainment criteria and thresholds applied. We aimed to estimate the prevalence of sarcopenia using two international definitions but employing Australian population-specific cut-points. METHODS: Participants (n = 665; 323 women) aged 60-96 years old were from the Geelong Osteoporosis Study. Handgrip strength (HGS) was measured by dynamometers and appendicular lean mass (ALM) by whole-body dual-energy X-ray absorptiometry. Physical performance was assessed using gait speed (GS, men only) and/or the timed up-and-go (TUG) test. Using cut-points equivalent to two standard deviations (SDs) below the mean young reference ran..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council (NHMRC), Australia


Awarded by NHMRC Career Development Fellowship


Awarded by NHMRC Investigator Grant


Funding Acknowledgements

The Geelong Osteoporosis Study was funded by the National Health and Medical Research Council (NHMRC), Australia (projects 251638 and 628582). S.X.S. was supported by a Deakin Postgraduate Scholarship in conjunction with the Geelong Medical and Health Benefits Association (GMHBA). K.L.H.-K. was supported by an Alfred Deakin Postdoctoral Research Fellowship, N.K.H. by a Dean's Research Postdoctoral Fellowship (Deakin University) and L.J.W. by an NHMRC Career Development Fellowship (1064272) and an NHMRC Investigator Grant (1174060). The funding organizations played no role in the design or conduct of the study, in the collection, management, analysis and interpretation of the data, nor in the preparation, review and approval of the manuscript.