Effects of Caffeine on Brown Adipose Tissue Thermogenesis and Metabolic Homeostasis: A Review
Lachlan Van Schaik, Christine Kettle, Rodney Green, Helen R Irving, Joseph A Rathner
FRONTIERS IN NEUROSCIENCE | FRONTIERS MEDIA SA | Published : 2021
The impact of brown adipose tissue (BAT) metabolism on understanding energy balance in humans is a relatively new and exciting field of research. The pathogenesis of obesity can be largely explained by an imbalance between caloric intake and energy expenditure, but the underlying mechanisms are far more complex. Traditional non-selective sympathetic activators have been used to artificially elevate energy utilization, or suppress appetite, however undesirable side effects are apparent with the use of these pharmacological interventions. Understanding the role of BAT, in relation to human energy homeostasis has the potential to dramatically offset the energy imbalance associated with obesity...View full abstract
Support of the research contributing to this review: Defence Science Institute (LSV).