Journal article

Candidemia in Children A 16-year Longitudinal Epidemiologic Study

Eloise J Silvester, Melissa MY Watanabe, Laure F Pittet, Alison Boast, Penelope A Bryant, Gabrielle M Haeusler, Andrew J Daley, Nigel Curtis, Amanda Gwee

PEDIATRIC INFECTIOUS DISEASE JOURNAL | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

Abstract

BACKGROUND: Candida species are the most common cause of systemic fungal infections in children. Risk factors for candidemia vary in different patient populations, posing challenges for clinical prediction of infection. We describe the epidemiology and clinical disease of candidemia in children admitted to a tertiary pediatric hospital. METHODS: Retrospective audit of children ≤18 years of age with candidemia at a tertiary pediatric hospital over a 16-year period. RESULTS: There were 139 episodes of candidemia in 124 children. A central venous catheter was present in 94% of episodes, prior antibiotic exposure in 86% and parenteral nutrition in 43%. During the study period, the proportion of ..

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