Journal article

The Relationship between Oxidative Stress and Anxiety in a Healthy Older Population

Karen Savage, Davy Kingshott, Andrew Gubko, Alicia Wt Three, Tamer Burjawi, Kevin Croft, Jerome Sarris, Con Stough

Experimental Aging Research | TAYLOR & FRANCIS INC | Published : 2021


Background/study context: F2-Isoprostanes are putative markers of oxidative stress, one of the processes associated with biological senescence. Evidence exists for elevated F2-Isoprostanes in chronic conditions including psychiatric disorders. Few studies have examined the relationship between oxidative stress and mood in older healthy samples, to establish the influence on mental health. Given current aging demographics in many nations, management of brain and mental health is crucial for longevity, chronic disease management, and quality of life.Method: We investigated the relationship between F2-Isoprostanes, a marker for oxidative stress, and anxiety and mood in 262 healthy adults aged 6..

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University of Melbourne Researchers


Awarded by NHMRC Clinical Research Fellowship

Funding Acknowledgements

JS is supported by an NHMRC Clinical Research Fellowship (APP1125000).