Journal article

Automated estimation of ischemic core prior to thrombectomy: comparison of two current algorithms

Lakshini Gunasekera, Leonid Churilov, Peter Mitchell, Andrew Bivard, Gagan Sharma, Mark W Parsons, Bernard Yan



PURPOSE: Endovascular thrombectomy (EVT) improves clinical outcomes in ischemic stroke with large vessel occlusion. Clinical benefits are inversely proportional to size of the pre-treatment ischemic core. This study compared estimated ischemic core volumes by two different CT perfusion (CTP) automated algorithms to the gold standard follow-up infarct volume using diffusion-weighted imaging (DWI) to assess for congruence, and thus eligibility for EVT. METHODS: Retrospective, single-center cohort study of 102 patients presenting to a comprehensive stroke center between 2012 and 2018. Inclusion criteria were CT perfusion prior to EVT, successful EVT with mTIBI 2b-3 reperfusion, and DWI post-EVT..

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