Journal article
T34. THE IMPACT OF ANTIDEPRESSANT USE ON THE TRANSITION TO PSYCHOSIS RATE IN THE NEURAPRO TRIAL
Monika Schlögelhofer, Patrick D McGorry, Barnaby Nelson, Maximus Berger, Connie Markulev, Hok Pan Yuen, Miriam R Schäfer, Nilufar Mossaheb, Stefan Smesny, Ian B Hickie, Gregor Berger, Eric YH Chen, Lieuwe De Haan, Dorien Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Andrew Thompson, Alison Yung, G Paul Amminger
Schizophrenia Bulletin | Oxford University Press (OUP) | Published : 2020
Abstract
Abstract Background Over the last two decades, several randomised controlled trials (RCTs) have indicated that preventive psychosocial, pharmacologic (Van der Gaag et al. 2013), and nutritional interventions (Amminger et al. 2010) are likely to be beneficial in people at ultra-high risk (UHR) of psychosis, in terms of delaying or preventing a transition to psychosis. Antidepressant medication is commonly prescribed in young people at UHR for psychosis; however, the evidence regarding its efficacy for psychosis prevention is limited (Fusar-Poli et al. 2007; Cornblatt et al. 2007; Fusar-Poli et al. 2015). The main aim of the present study is ..
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