Journal article
T239. SINGLE-SUBJECT PREDICTION OF FUNCTIONAL OUTCOMES IN CLINICAL HIGH RISK SUBJECTS USING CLINICAL DATA
Marlene Rosen, Nathalie Kaiser, Theresa Haidl, Mauro Seves, Frauke Schultze-Lutter, Stefan Borgwardt, Paolo Brambilla, Eva Meisenzahl, Christos Pantelis, Stephan Ruhrmann, Raimo Salokangas, Rachel Upthegrove, Stephen Wood, Nikolaos Koutsouleris
Schizophrenia Bulletin | Oxford University Press (OUP) | Published : 2018
Open access
Abstract
Psychotic disorders are associated with serious deterioration in functioning even before the first psychotic episode. Also on clinical high risk (CHR) states of developing a first psychotic episode, several studies reported a decreased global functioning. In a considerable proportion of CHR individuals, functional deterioration remains even after (transient) remission of symptomatic risk indicators. Furthermore, deficits in functioning cause immense costs for the health care system and are often more debilitating for individuals than other symptoms. However in the past, CHR research has mostly focused on clinical outcomes like transition and therefore, functioning in CHR patients is under-in..
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