Executive function mediates the prospective association between neurostructural differences within the central executive network and anti-social behavior after childhood traumatic brain injury
Nicholas P Ryan, Cathy Catroppa, Nathan Hughes, Felicity L Painter, Stephen Hearps, Miriam H Beauchamp, Vicki A Anderson
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY | WILEY | Published : 2021
BACKGROUND: Despite increasing evidence of a link between early life brain injury and anti-social behavior, very few studies have assessed factors that explain this association in children with traumatic brain injury (TBI). One hypothesis suggests that childhood TBI elevates risk for anti-social behavior via disruption to anatomically distributed neural networks implicated in executive functioning (EF). In this longitudinal prospective study, we employed high-resolution structural neuroimaging to (a) evaluate the impact of childhood TBI on regional morphometry of the central executive network (CEN) and (b) evaluate the prediction that lower EF mediates the prospective relationship between st..View full abstract
This work was supported by a grant from the Victoria Neurotrauma Initiative, Australia (No. CO6E1); the Victorian Government Operational Infrastructure Support Program; and an NHMRC Senior Practitioner Fellowship to VA. The authors have declared that they have no competing or potential conflicts of interest.