Association of age at myopia onset with risk of high myopia in adulthood in a 12-year follow-up of a chinese cohort

Abstract

IMPORTANCE Early-onsetmyopia is well known to progress to highmyopia in adulthood. However, no accurate estimation of how a specific age atmyopia onset is associated with the probability of developing highmyopia in adulthood is available, and a very-long-term follow-up study with data from annual visits is needed. OBJECTIVE To estimate the risk of developing highmyopia in adulthood associated with a specific age atmyopia onset from a data set with a 12-year annual follow-up. DESIGN, SETTING, AND PARTICIPANTS This ongoing, population-based prospective cohort study of twins was conducted in Guangzhou, China, on July 11, 2006. Data from baseline to August 31, 2018, were analyzed. The first-born..