Conference Proceedings

316 - Lewy Body Study: An Australian longitudinal biomarker study of dementia with Lewy bodies

Kai Sin Chin, Nawaf Yassi, Zina Hijazi, Victor Villemagne, Christopher Rowe, Colin L Masters, Rosie Watson

International Psychogeriatrics | Cambridge University Press (CUP) | Published : 2020

Abstract

Background:Cerebral multi-morbidity is common in older people with dementia, including people with dementia with Lewy bodies (DLB). We describe the first Australian-based, longitudinal observational biomarker study of DLB.Aims:To investigate the frequency and influence of Alzheimer’s disease (AD) pathology (amyloid-β and tau) and cerebrovascular disease on clinical symptoms and disease outcome in DLB.Methods:The study will recruit 100 people with mild to moderate probable DLB, who will undergo comprehensive clinical and cognitive assessments. Scales targeting DLB-specific clinical features (such as cognitive fluctuations and rapid eye movement sleep behaviour disorder) are administered. Biom..

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