Burden of Hospitalization in Young-Onset Type 2 Diabetes—The Hong Kong Diabetes Register

Abstract

Objective: Young-onset type 2 diabetes (YOD, defined as age <40 years) is associated with early β-cell failure and poor risk factor control. While YOD incidence is increasing rapidly, its disease burden is poorly understood, resulting in clinical inertia and poor treatment adherence. We examined the burden of hospitalization among Chinese adults with YOD. Methods: We conducted a prospective cohort study measuring all-cause hospitalization in YOD and usual-onset type 2 diabetes (T2D) among adults aged 20-75 years using the Hong Kong Diabetes Register (2000-2015, n=21,779). We estimated the impacts of YOD and risk factor control on hospitalization rate after T2D diagnosis usi..