Journal article

New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies

Kirsten C Morley, Christina J Perry, Joshua Watt, Tristan Hurzeler, Lorenzo Leggio, Andrew J Lawrence, Paul Haber

Expert Opinion on Pharmacotherapy | TAYLOR & FRANCIS LTD | Published : 2021


introduction: The number of medications approved for AUD is small and they generally have limited efficacy. We need new pharmacotherapies for the management of AUD.Areas covered: In this review, the authors aim to synthesise literature for new approved and emerging pharmacotherapies for AUD. Recently approved medications include nalmefene, which was approved in Europe and Australia for the purposes of controlled drinking. Baclofen has also been approved in France but not in other countries. Off label medications including topiramate and gabapentin have received significant attention with multiple RCTs and meta-analyses and have widespread use in several countries including the USA. Several n..

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Funding Acknowledgements

K Morley is supported by the NSW Health Fellowship. P Haber is supported by the NHMRC Practitioner Research Fellowship, while L. Leggio has received support from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute of Drug Abuse.