Journal article
Working Memory Training Is Associated with Changes in Resting State Functional Connectivity in Children Who Were Born Extremely Preterm: a Randomized Controlled Trial
CEJ Tseng, L Pascoe, G Roberts, LW Doyle, KJ Lee, DK Thompson, M Seal, EK Josev, J Chen, C Nosarti, PJ Anderson
Journal of Cognitive Enhancement | SPRINGERNATURE | Published : 2019
Abstract
Children born extremely preterm (EP; < 28 weeks of gestation) or extremely low birth weight (ELBW; < 1000 g) are at increased risk of working memory deficits compared with their term-born peers and may benefit from working memory training. This study aimed to determine whether Cogmed Working Memory Training®, compared with a placebo training program, was associated with changes in resting-state functional connectivity (rsfc) and whether these changes correlated with working memory performance in EP/ELBW children. Twenty-one 7-year-old EP/ELBW children were enrolled in a double-blinded randomized controlled trial and had magnetic resonance imaging (MRI) assessments (Cogmed, n = 12; placebo (a..
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Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
This study was supported by the Murdoch Children's Research Institute, the Royal Children's Hospital, The Royal Children's Hospital Foundation, the Department of Paediatrics at The University of Melbourne, Monash University, and the Victorian Government's Operational Infrastructure Support Program. This study was also supported by the Australian National Health and Medical Research Council (NHMRC: Project Grant 1028422, Centre of Research Excellence in Newborn Medicine (1060733), Program Grant 606789, Senior Research Fellowship 1081288, Career Development Fellowship 1085754). This article was made open access with the financial support of King's College London.