F158. FUNCTIONAL CONNECTIVITY DIVERSITY OF THE INSULA CORTEX IN SCHIZOPHRENIA: SUBREGIONS OR CONTINUA?

Abstract

The function, cytoarchitecture and connectivity of the insula cortex are diverse. Cluster analyses have been applied to functional magnetic resonance imaging (MRI) connectivity data to parse this diversity and subdivide the insula into discrete subregions. However, the number of subregions comprising the insula remains vexed and whether these putative subregions are disturbed in neuropsychiatric illness are unknown. The present study aimed to (i) rigorously evaluate the number of subregions (if any) into which the insula can be subdivided based on topographic variation in whole-brain patterns of insula functional connectivity; and, (ii) establish whether the connectional topography of the in..