Journal article

Exercise physiology in cirrhosis and the potential benefits of exercise interventions: A review

Jack West, Paul J Gow, Adam Testro, Brooke Chapman, Marie Sinclair

Journal of Gastroenterology and Hepatology | WILEY | Published : 2021

Abstract

Reduction in muscle mass is a highly prevalent phenomenon in cirrhosis and is now well-documented to be associated with significant morbidity and mortality. Research into muscle loss in cirrhosis remains limited by an ongoing poor understanding of its relationship with muscle function, physical activity and aerobic capacity. Alterations in exercise physiology have been documented in studies of individuals with cirrhosis that provide important information on physical function that is not captured by simple quantification of muscle mass. Despite expert consensus recommending regular exercise in end-stage liver disease to maintain muscle mass and function, there is little evidence guiding clini..

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