Journal article
Community intervention for child tuberculosis active contact investigation and management: study protocol for a parallel cluster randomized controlled trial
A Vasiliu, S Eymard-Duvernay, B Tchounga, D Atwine, E de Carvalho, S Ouedraogo, M Kakinda, P Tchendjou, S Turyahabwe, AK Kuate, G Tiendrebeogo, PJ Dodd, SM Graham, J Cohn, M Casenghi, M Bonnet
Trials | BMC | Published : 2021
Open access
Abstract
Background: There are major gaps in the management of pediatric tuberculosis (TB) contact investigation for rapid identification of active tuberculosis and initiation of preventive therapy. This study aims to evaluate the impact of a community-based intervention as compared to facility-based model for the management of children in contact with bacteriologically confirmed pulmonary TB adults in low-resource high-burden settings. Methods/design: This multicenter parallel open-label cluster randomized controlled trial is composed of three phases: I, baseline phase in which retrospective data are collected, quality of data recording in facility registers is checked, and expected acceptability an..
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Funding Acknowledgements
Unitaid is funding the CaP TB project through EGPAF. For the CONTACT research study, EGPAF is using the funding through IRD. The funding document available with the submission of this manuscript is the letter between EGPAF and Institut Buisson Bertrand, a management center for the IRD. The funding body has no role in study design, data collection, or writing the manuscript. EGPAF (Dr Appolinaire Tiam, Elizabeth Glaser Pediatric AIDS Foundation, 1140, Connecticut Av. Suite 200, NW, Washington, DC 20036) is the sponsor of the trial.