Journal article

Psychiatric symptoms are the strongest predictors of quality of life in patients with drug-resistant epilepsy or psychogenic nonepileptic seizures

Benjamin Johnstone, Charles B Malpas, Dennis Velakoulis, Patrick Kwan, Terence J O'Brien

Epilepsy & Behavior | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2021

Abstract

OBJECTIVE: This cross-sectional study aimed to determine the effect of psychiatric comorbidity and neurocognitive deficits on the quality of life in a cohort of patients admitted for Video-EEG Monitoring (VEM) for investigation into a presumed seizure disorder. METHODS: Patients were recruited from an inpatient VEM unit between January 2009 and December 2016. All patients had formal neuropsychiatric assessment. All patients completed questionnaires assessing psychiatric symptomatology (SCL-90-R), Anxiety and Depression (HADS), quality of life (QOLIE-89), and cognition (NUCOG). RESULTS: A total of 451 patients were enrolled. Upon discharge, 204 patients were diagnosed to have epilepsy, 118 ps..

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Grants

Awarded by Program Grants to Terence J. O'Brien from the National Health and Medical Research Council (NHMRC)


Funding Acknowledgements

The study was funded by a Program Grants to Terence J. O'Brien from the National Health and Medical Research Council (NHMRC) (grant number 566843) and from the Royal Melbourne Hospital Neuroscience Foundation. The remaining authors have no conflicts of interest.