Journal article

Psychiatric symptoms are the strongest predictors of quality of life in patients with drug-resistant epilepsy or psychogenic nonepileptic seizures.

Benjamin Johnstone, Charles B Malpas, Dennis Velakoulis, Patrick Kwan, Terence J O'Brien

Epilepsy & Behavior | Elsevier BV | Published : 2021


OBJECTIVE: This cross-sectional study aimed to determine the effect of psychiatric comorbidity and neurocognitive deficits on the quality of life in a cohort of patients admitted for Video-EEG Monitoring (VEM) for investigation into a presumed seizure disorder. METHODS: Patients were recruited from an inpatient VEM unit between January 2009 and December 2016. All patients had formal neuropsychiatric assessment. All patients completed questionnaires assessing psychiatric symptomatology (SCL-90-R), Anxiety and Depression (HADS), quality of life (QOLIE-89), and cognition (NUCOG). RESULTS: A total of 451 patients were enrolled. Upon discharge, 204 patients were diagnosed to have epilepsy, 118 ps..

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